Mural at St. Sabina by Fr. Fernando Arizti, SJ

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John 3:16

For God so loved the world that He gave His only son...

The two large hands represent the hands of God the Father who offers us the gift of His son. The Father's hands are cupped because a giver offers a gift, but the gift must be received or it remains in the giver's hands. Jesus' left hand is completely open, symbolizing His total self giving of His life for our salvation. His right hand is calling us to come follow Him.